Ask The NY Mast Cell Activation Syndrome (MCAS) Specialists: Dr. Tania Dempsey & Dr. Lawrence Af

I had melanoma that sat on my back (misdiagnosed as benign initially) for three years. I feel my Mast Cell disease was likely triggered by this and low vitamin D when I started avoiding the sun and using sunblock due to fear of melanoma reoccurrence. Is there any research showing a relationship with melanoma and vitamin D3 deficiency? Although mast cell disease sometimes develops in reaction to (i.e., secondary to) other problems (including cancers of a wide variety of sorts), there are published preliminary research data strongly suggesting the disease is primary in most patients who have it, and if that truly is the case, then it’s more likely that your mast cell disease was present before

Mast Cell Activation Syndrome (MCAS) Questions Answered: Dr. Tania Dempsey & Dr. Lawrence Afrin

What is the likelihood of inheriting Mast Cell Activation Disorder (MCAD)? As best as we presently understand, the likelihood of inheriting mastocytosis is extremely slim. As for inheriting MCAS, all that can be said at present, based on very limited available peer-reviewed, published data, is that that likelihood appears to be 50%, but when it happens, the affected child usually begins demonstrating symptoms at an earlier age than was seen in the affected parent, plus the affected child usually comes to be generally more severely afflicted by the disease than was seen in the affected parent. To be crystal clear, though, that estimate of 50% means that there are plenty of children of MCAS-

Ask The Mast Cell Activation Syndrome Doctors: MCAS Questions Answered by NYC MCAD Physicians Dr. Ta

Hi. I have MCAD. I have recently been also dx with chronic non-alcoholic pancreatitis. My GI doc questions whether mast cell disease and its subsequent inflammatory state is the culprit. Any thoughts? Due to the fact that the broad themes of the effects of the more than 200 mediators produced by the mast cell are inflammatory, allergic, and tissue growth/development effects, and given that mast cells are present in every organ/tissue/system in the body, it’s not surprising that mast cell activation syndrome (MCAS) is a disease of chronic multisystem unwellness of general themes of inflammation, allergic-type phenomena, and abnormalities (often, but not always, subtle) in growth and developm

Ask The Mast Cell Activation Doctors: MCAS Questions Answered by NY MCAS Specialists Dr. Tania Demps

My 24-year-old son has cutaneous mastocytosis. He is self-conscious. He has had spots since he was a little boy and continues to get more. Can he slow down additional skin "spots." Is it triggers that add more? Or will he always get more for the rest of his life just because he has the disorder? I’m sorry to hear of your son’s difficulties. In general, when the skin lesions of cutaneous mastocytosis become sufficiently bothersome (whether from a cosmetic or any other perspective), ultraviolet-light-based therapy (and there’s more than one specific approach to this which can be considered depending on the individual case) tends to be the most effective at reducing, at least for some time, th

Long Island Lyme Disease Testing

“Dear Dr. Dempsey, Our family just returned from a 10-day trip to the north fork of Long Island. We were staying at a beach house in the Peconic that we stay at every summer for almost two weeks. After we left yesterday, my friend went to the house with her family and this morning they found a deer tick on the rocking chair on the back porch. The owners did not spray and the lawn care folks did tell us the day before we left that there were ticks in the brush leading to the beach. My kids were playing on the back lawn, and porch the entire time we were there. They are 3 and 6. 
No one has signs of Lyme disease as of yet, and we checked the kids constantly. We all do have a few mosquito

Ask The Mast Cell Activation Syndrome Doctors: Dr. Tania Dempsey & Dr. Lawrence Afrin

Can you explain why seizures during Anaphylaxis happen? Does our Nervous System shutdown? Not enough oxygen to the brain? Preferably non-Epileptic as there is already enough information about those. When you have Autonomic or unknown seizures you're looked at like you're a mental patient. I only have seizures during Anaphylaxis and I've always been curious to know what happens during the reactions that they happen. The specific mechanism by which anaphylaxis in a given patient can also cause seizure activity in the brain is unclear. It’s probably not even a matter of just a single such mechanism, and instead there likely are multiple mechanisms by which this can happen (for example, release

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